Heterocyclics as Inducers of Apoptosis

来自 : link.springer.com/chapter/10.1 发布时间：2021-03-25

Abstract

A discussion on apoptosis and a variety of heterocyclic compounds that induce apoptosis is presented. A number of heterocyclic compounds containing nitrogen, oxygen or both exhibit significant anticancer properties. Brief discussions on the mode of action of various anticancer heterocyclic compounds in inducing apoptosis are also presented.

KeywordsEpidermal Growth Factor Receptor Human Cancer Cell Line Tubulin Polymerization Quinoline Derivative A549 Lung Cancer Cell  These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves. This is a preview of subscription content, log in to check access.ReferencesAlan PK, Irina NG, Franck G, Andrei VO, Kim KH, Toru K, Songpo G, Denise H, Doris NL, Sylvie YB, Daniel DB (2009) From a natural product lead to the identification of potent and selective benzofuran-3-yl-(indol-3-yl)maleimides as glycogen synthase kinase 3β inhibitors that suppress proliferation and survival of pancreatic cancer cells. J Med Chem 52:1853–1863. doi: 10.1021/jm801317h CrossRefGoogle ScholarAlessandra B, Maria M, Silvia G, Angela R, Manlio T, Luisa D (2008) Multidrug resistance reverting activity and antitumor profile of new phenothiazine derivatives. 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